Protein Alignment H2.0 and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_113925.1
• Gene: Nkx6-1 / 65193
• RGDID: 69318
• Length: 365
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 94/387 - (24%)
• Similarity: 127/387 - (32%)
• Gaps: 139/387 - (35%)

  Fly    13 SMPENLSTHMYGECEVNPTLAKCPDPVNVDHELPTKESCASTTIVSTSPTSATSTTKVKLSFSVD 77
            |.|:.||             |..|..:|.....|:....:...:.|.||:.::|:
  Rat    85 SPPQQLS-------------AATPHGINDILSRPSMPVASGAALPSASPSGSSSS---------- 126

  Fly    78 RLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANAESRRFGHATLPPTFTPTSSHTY 142
                         ||||.|..|....:..|..      :.|.|.|...|.....|.|:..|....
  Rat   127 -------------SSSSASATSASAAAAAAAA------AAAAAASSPAGLLAGLPRFSSLSPPPP 172

  Fly   143 PFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPK 207
            |        ||.|.        :|..||..|...||
  Rat   173 P--------PGLYF--------SPSAAAVAAVGRYP----------------------------- 192

  Fly   208 HLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSP--AAAAAATSQ 270
                  ||           ||.|.               |:||.....:..:.|  .|..|.|..
  Rat   193 ------KP-----------LAELP---------------GRTPIFWPGVMQSPPWRDARLACTPH 225

  Fly   271 NGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLT 335
                       ||:.....:||||.  :|..||..|...||..|:|.||:..|:|.:||..|.:|
  Rat   226 -----------QGSILLDKDGKRKH--TRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMT 277

  Fly   336 DAQVKVWFQNRRMKWR--HTRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTPQEALDYSSD 395
            ::||||||||||.|||  |..| :.:.::||.|......|.  :.....|....:.||.:||
  Rat   278 ESQVKVWFQNRRTKWRKKHAAE-MATAKKKQDSETERLKGT--SENEEDDDDYNKPLDPNSD 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/52 (52%)
Nkx6-1	NP_113925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		17/86 (20%)
		Repressor domain. /evidence=ECO:0000250	102..269		59/285 (21%)
		Homeobox	240..294	CDD:395001	28/53 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		11/45 (24%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		8/32 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910