DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment H2.0 and DRGX

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:XP_011538391.1 Gene:DRGX / 644168 HGNCID:21536 Length:298 Species:Homo sapiens


Alignment Length:159 Identity:51/159 - (32%)
Similarity:69/159 - (43%) Gaps:56/159 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   283 GNASAG--SNG--KRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLTDAQV- 339
            ||.|:|  .:|  :||:..:|..|:..|.:.||..|.|..|   ||   |.:||.::|||:|:| 
Human    17 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHY---PDVFTREELAMKINLTEARVQ 78

  Fly   340 ----------------------------------KVWFQNRRMKWRHTRENLKSGQE---KQPSA 367
                                              :|||||||.|||.| |...|.||   |:|.|
Human    79 LANSCLKTELQIEINDTIIEHSEVEDHNFSLKGARVWFQNRRAKWRKT-ERGASDQEPGAKEPMA 142

  Fly   368 ---VPESGGVFKTSTPSGD--GTPQEALD 391
               .|....:  .|.|.||  .:.:|||:
Human   143 EVTPPPVRNI--NSPPPGDQARSKKEALE 169

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 26/90 (29%)
DRGXXP_011538391.1 Homeobox 37..124 CDD:278475 26/89 (29%)
OAR 236..252 CDD:281777
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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