Protein Alignment H2.0 and lbx2

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001007135.1
• Gene: lbx2 / 64276
• ZFINID: ZDB-GENE-001206-2
• Length: 257
• Species: Danio rerio
• Alignment Length: 240
• Identity: 70/240 - (29%)
• Similarity: 98/240 - (40%)
• Gaps: 52/240 - (21%)

  Fly   215 PPPHNSTTASALLAPL------------HSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAA--- 264
            |||.||...   |.|.            .|:.||...:..::..|.:..:....||:||..|
Zfish    30 PPPANSNKP---LTPFSIEDILNKPSVKKSVGSLCPPRVLEKVTGSSASRNGISAPSSPLCALEE 91

  Fly   265 -AAATSQ-------NGAHG--HGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKY 319
             |:.|.:       ..|.|  |....||..||      :||..||..|:|.|...||.:|..|||
Zfish    92 LASKTFKGLEVSVIQAAEGREHINAFGQRQAS------KKRRKSRTAFTNHQIYELEKRFLYQKY 150

  Fly   320 ITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPES------------- 371
            ::..||.::|.:|.||:|||..||||||.|.:...|.:|:..|......|::
Zfish   151 LSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIPPQALQKLVSMEDMEDA 215

  Fly   372 -GGVFKTSTPSGDGTPQEALDYSSDSCSSVDLSEQADEDDNIEIN 415
             ||    |.|........|...|..|.......|.::||:.||::
Zfish   216 HGG----SGPISPSLSPRAFPQSPSSSRGQTTDEFSEEDEEIEVD 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/52 (52%)
lbx2	NP_001007135.1	Required for convergent extension movement and hypaxial myogenesis during gastrulation. Required for the formation of thick and thin myofilaments. Required for myod1 expression in the pectoral fin bud. Required for continuous expression of cxcl12a in the posterior lateral mesoderm at the tail bud stage and in adaxial cells at the 10-somite stage. /evidence=ECO:0000269|PubMed:19216761, ECO:0000269|PubMed:22216300, ECO:0000269|PubMed:22406073	1..46		7/18 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		7/15 (47%)
		Homeobox	129..183	CDD:395001	27/53 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..257		12/55 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810