DRSC/TRiP Functional Genomics Resources

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Protein Alignment H2.0 and nkx2.4b

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_571664.1 Gene:nkx2.4b / 58112 ZFINID:ZDB-GENE-000830-1 Length:307 Species:Danio rerio


Alignment Length:297 Identity:76/297 - (25%)
Similarity:114/297 - (38%) Gaps:60/297 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 HTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQH 204
            |:.||...|.|.|......|.....:   :|..|:|.|.....:      |...|||...|:..|
Zfish     7 HSTPFSVSDILSPIEETFKKFAAMES---SASLASPLYRQSQVS------QANLQQHSMSHNAYH 62

  Fly   205 HPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQR-------FLGKTPQQLLDIAPTSPA 262
            .|   |.|..    :||........:.::..|...|:..|       :.|..|:...   ||...
Zfish    63 MP---HSQFS----HSTMGGYCNGTIGAMGDLPSYQESMRNGATATAWYGSNPEPRY---PTISR 117

  Fly   263 AAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRK 327
            ....:...|.....|....:...:..:..:|||   |.:||..|...||.:|:||||::.|:|..
Zfish   118 FMGPSAGMNMGTLPGMDASKSMVTLHAAPRRKR---RVLFSQAQVYELERRFKQQKYLSAPEREH 179

  Fly   328 LAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTP------------ 380
            ||:.::||..|||:||||.|.|.:...::..|.|:       :||.:....:|            
Zfish   180 LASMIHLTPTQVKIWFQNHRYKMKRQAKDKASQQQ-------DSGNMCAQQSPRRVALPVLVKDG 237

  Fly   381 ----SGDGTP-------QEALDYSSDSCSSVDLSEQA 406
                :|.|||       |..|. |....|:.||.|.:
Zfish   238 KPCQNGSGTPTPIHQQVQSVLG-SETLASAEDLEEMS 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 26/52 (50%)
nkx2.4bNP_571664.1 Homeobox 150..203 CDD:278475 27/55 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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