DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and hoxa3a

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_571609.1	Gene:	hoxa3a / 58049	ZFINID:	ZDB-GENE-000823-3	Length:	411	Species:	Danio rerio

Alignment Length:	276	Identity:	62/276 - (22%)
Similarity:	110/276 - (39%)	Gaps:	76/276 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 YMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHN 219
            |.|..::....|.::|            |.|  .:...:||:.|..|.:      .:.|:|.  .
Zfish     6 YCDGSAIYSGLPYQSA------------NGL--GYDASQQQYLQALHAE------SEYHRPA--C 48

  Fly   220 STTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIA-----PTSPAAAAAATS---------- 269
            |..:..:.|.||  ||.::::..|:..| |...:.|.:     ||:|:..::.:|
Zfish    49 SLQSPGISAGLH--TSNEMSEVCQQING-TQATVTDTSDNKQPPTAPSGPSSPSSLNQIPNIDSA 110

  Fly   270 -QNGAHGHGGGN------------------------------GQGNASAGSNGKRKRSWSRAVFS 303
             :|..|.....:                              |:..:..||...::   :|..::
Zfish   111 AKNPVHVSPTPSTRKHIFPWMKESRQNTKQKSCSIISVESCAGRQKSPPGSAASKR---ARTAYT 172

  Fly   304 NLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAV 368
            :.|...||.:|...:|:.:|.|.::|..||||:.|:|:||||||||::..::.|  |....|.|.
Zfish   173 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGL--GMMPSPGAQ 235

  Fly   369 PESGGVFKTSTPSGDG 384
            .....|..:|...|.|
Zfish   236 SPHSPVSLSSGGGGGG 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	23/52 (44%)
hoxa3a	NP_571609.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..126		7/46 (15%)
		Antp-type hexapeptide	127..132		0/4 (0%)
		Homeobox	168..220	CDD:278475	23/51 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	223..250		6/28 (21%)
		DUF4074	347..409	CDD:290032
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910