DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and lhx9

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001032320.2	Gene:	lhx9 / 550405	ZFINID:	ZDB-GENE-050417-210	Length:	396	Species:	Danio rerio

Alignment Length:	190	Identity:	50/190 - (26%)
Similarity:	66/190 - (34%)	Gaps:	74/190 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 GGG------NGQGNASAGSNGKRKR--------SWS---------------------------RA 300
            |||      ||.|....|...|||.        |:|                           |.
Zfish   208 GGGLALPYFNGTGTVQKGRPRKRKSPAMGIDIGSYSSGCNENDADHLDRDQQPYPPSQKTKRMRT 272

  Fly   301 VFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQP 365
            .|.:.|.:.::..|.........|.::||.:..||...::|||||.|.|:|  |..|:.
Zfish   273 SFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFR--RNVLRQ------ 329

  Fly   366 SAVPESGGVFK---TSTP-----SGDGTPQEALDYSSDSCSSVDLSEQADEDDNIEINVV 417
                |:|||.|   ||.|     ||..||      .|.:.:..||:       |..|.||
Zfish   330 ----ENGGVDKADGTSLPPPSSDSGALTP------PSTATTLTDLT-------NPSITVV 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	17/79 (22%)
lhx9	NP_001032320.2	LIM1_Lhx2	61..124	CDD:188853
		LIM2_Lhx2_Lhx9	129..187	CDD:188763
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..272		0/23 (0%)
		Homeobox	271..323	CDD:278475	16/51 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..365		14/52 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	377..396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910