DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and hoxb3

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001015971.1	Gene:	hoxb3 / 548725	XenbaseID:	XB-GENE-482576	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	68/270 - (25%)
Similarity:	103/270 - (38%)	Gaps:	84/270 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 PPTFTPTSSHTYPFVGLDKLF------------PGPYMDYK----SVLRPTPIRAAEHAAPTYPT 179
            |....|||||      :|..|            .||.:..|    |.:||.  .::|.:.|..||
Frog    28 PQQSFPTSSH------MDNEFQRSSCSLQSLGHSGPLVKAKNLNGSCMRPN--LSSEQSQPLSPT 84

  Fly   180 LATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNS----TTASALLAPLHSLTSLQLTQ 240
            ...::.......|.                 ...||.|..|    :.||..:.|       .:.:
Frog    85 ANPSSNTNSSSSQA-----------------SLSKPSPAKSQASGSPASKQIFP-------WMKE 125

  Fly   241 QQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNL 305
            .:|....|:       :|.:|||.:.          ||......:||.     ||  :|..:::.
Frog   126 SRQNSKQKS-------SPPAPAAESC----------GGDRSPPGSSAS-----KR--ARTAYTSA 166

  Fly   306 QRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPE 370
            |...||.:|...:|:.:|.|.::|..|||::.|:|:||||||||::.        .:|.......
Frog   167 QLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKK--------DQKVKGMSSS 223

  Fly   371 SGGVFKTSTP 380
            |||...||||
Frog   224 SGGASPTSTP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	22/52 (42%)
hoxb3	NP_001015971.1	Homeobox	160..212	CDD:306543	22/51 (43%)
hoxb3	NP_001015971.1	DUF4074	325..384	CDD:315871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910