Protein Alignment H2.0 and NKX1-1

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 145
• Identity: 48/145 - (33%)
• Similarity: 68/145 - (46%)
• Gaps: 36/145 - (24%)

  Fly   250 PQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWS----------RAVFSN 304
            |::...:|...|..|||.       |..|...||.|:| :..||||:.|          |..|:.
Human   249 PRENSPVAQGPPGGAAAP-------GGAGTTPQGTATA-AKPKRKRTGSDSKSGKPRRARTAFTY 305

  Fly   305 LQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVP 369
            .|...||.:|:..:|::..:|..||..|:||:.|||:||||||.||:          ::.|.|
Human   306 EQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK----------KQNPGA-- 358

  Fly   370 ESGGVFKTSTPSGDG 384
                  .||.|:|.|
Human   359 ------DTSAPTGGG 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	24/62 (39%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	23/51 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900