Protein Alignment H2.0 and PAX4

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 66/250 - (26%)
• Similarity: 95/250 - (38%)
• Gaps: 52/250 - (20%)

  Fly   153 GPYMDYKS-VLRPTPIRAAEHAAPTYPTLATNALLRFH-------QHQKQQHQQHHHHQHHPKHL 209
            |.|  |:: ||.|..|..::....|.|.:|..|.|:..       :.|:|...:         .|
Human    59 GRY--YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAE---------GL 112

  Fly   210 HQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAH 274
            ..|.|.|     :.|::...|.:|      |:.|   |....:|...|..:||.....:......
Human   113 CTQDKTP-----SVSSINRVLRAL------QEDQ---GLPCTRLRSPAVLAPAVLTPHSGSETPR 163

  Fly   275 GHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQV 339
            |...|.|..|              |.:||..|.:.||.:||:.:|.....|.|||...:|.:..|
Human   164 GTHPGTGHRN--------------RTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTV 214

  Fly   340 KVWFQNRRMKWRHTRENLKSGQE----KQPSAVPESGGVFKTSTPSGDGTPQEAL 390
            :|||.|||.|||. :|.||...:    .|...||.......::..|....|..||
Human   215 RVWFSNRRAKWRR-QEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAAL 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	22/52 (42%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	19/85 (22%)
		Homeobox	174..226	CDD:306543	22/51 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910