DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Dlx6

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_008760963.2	Gene:	Dlx6 / 500023	RGDID:	1561539	Length:	298	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	74/269 - (27%)
Similarity:	104/269 - (38%)	Gaps:	95/269 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 NALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPP-------PHNSTTASALLA---PLHSLTSLQ 237
            :|.:.|.|.|:||.||....|...:...||..||       ||:..|:.|:..   |||.|.|
  Rat    19 SAFMEFGQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPQPHSQQTSPAMAGAHYPLHCLHS-- 81

  Fly   238 LTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGH---------GGGNGQG---------- 283
                                  :.||||||.|.:..|.|         ||||...
  Rat    82 ----------------------AAAAAAAAGSHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYM 124

  Fly   284 -------------NASAGS----------------------NGKRKR-SWSRAVFSNLQRKGLEI 312
                         |:||.:                      |||.|: ...|.::|:||.:.|..
  Rat   125 SHSQHSPYLQSYHNSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNH 189

  Fly   313 QFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKT 377
            :|||.:|:..|:|.:|||.|.||..|||:||||:|.|::...:...:..|..|  :|.|..:
  Rat   190 RFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDP--LPGSAAL--- 249

  Fly   378 STPSGDGTP 386
             :|.....|
  Rat   250 -SPRSPALP 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	26/52 (50%)
Dlx6	XP_008760963.2	COG5576	124..280	CDD:227863	39/140 (28%)
Dlx6	XP_008760963.2	Homeobox	175..229	CDD:395001	26/53 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910