DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and alx4b

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001297007.1	Gene:	alx4b / 497424	ZFINID:	ZDB-GENE-050208-140	Length:	259	Species:	Danio rerio

Alignment Length:	197	Identity:	43/197 - (21%)
Similarity:	59/197 - (29%)	Gaps:	61/197 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 PTFTPTSSHTY------PF-----VGLDKLFPGPYMDYKSVL-RPTPIRAAEHAAPTYPTLATNA 184
            |||.|....||      ||     ...|....|.|..|...: ||.....:|.:     .|...|
Zfish    47 PTFLPAKGQTYGEKPRSPFHQDCPTLDDSTAEGAYSKYHLFMQRPACKSPSEDS-----KLEDGA 106

  Fly   185 LL-----------------RFHQHQKQQHQQHHHHQH------HPKHLHQQHKPP-PHNSTTASA 225
            |:                 ||  .|.||.:.|....:      .|::..|...|. ...|::||.
Zfish   107 LISCYGVVSESPGKWRKRERF--GQMQQVRTHFSTAYELPLLTRPENYAQIQNPSWLSGSSSASP 169

  Fly   226 L---LAPLHSLTSLQLTQQQQR-----FLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQ 282
            :   :.|..:::|.........     |||.          .||..:.|.|......|..|..|.
Zfish   170 VPGCVVPCDTVSSCMTPHPHSASGVSDFLGM----------PSPGGSMAQTHMGSLFGSSGVGGT 224

  Fly   283 GN 284
            .|
Zfish   225 IN 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475
alx4b	NP_001297007.1	OAR	235..252	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910