DRSC/TRiP Functional Genomics Resources

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Protein Alignment H2.0 and Pbx4

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001101869.1 Gene:Pbx4 / 361131 RGDID:1305100 Length:379 Species:Rattus norvegicus


Alignment Length:315 Identity:59/315 - (18%)
Similarity:99/315 - (31%) Gaps:120/315 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 ESRRFGHATLPPTFTP-------TSSHTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYP 178
            |.|..|.|....|.||       :..|:               ||::.|  :.||...|:     
  Rat   104 EKRGRGGAAAGSTATPGGCPNDNSIEHS---------------DYRAKL--SQIRQIYHS----- 146

  Fly   179 TLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSL---QLTQ 240
                       :.:|.:........|....|.:|.:..|.:|.....:::.:||..|.   ||.|
  Rat   147 -----------ELEKYEQACREFTTHVTNLLREQSRVRPVSSGEIEHMVSTIHSKFSAIQRQLKQ 200

  Fly   241 Q--------QQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSW 297
            .        :.|||                                           :.:|||  
  Rat   201 STCEAVMTLRSRFL-------------------------------------------DARRKR-- 220

  Fly   298 SRAVFSNLQRKGLEI------QFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTREN 356
                 .|..::..|:      ......|.::..:.:||.:..:|.:||..||.|:|:::   ::|
  Rat   221 -----RNFSKQATEVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGNKRIRY---KKN 277

  Fly   357 LKSGQEKQPSAVPESGGVFKTSTPSG----DGTPQEALDYSSDSCSSVDLSEQAD 407
            ....||:......::..|.||....|    ..||      |.|||....|:..:|
  Rat   278 TGKFQEEATMYTGKTSTVTKTRVSGGQTSCQSTP------SPDSCGPFPLTSGSD 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 12/58 (21%)
Pbx4NP_001101869.1 PBC 25..215 CDD:281746 29/186 (16%)
homeodomain 217..277 CDD:238039 15/69 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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