Protein Alignment H2.0 and HOXC8

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 60/232 - (25%)
• Similarity: 89/232 - (38%)
• Gaps: 46/232 - (19%)

  Fly   168 RAAEHAAPTYPTLATNALLRFHQHQKQQH----------QQHHHHQHHPKHLHQQHKPPPHNSTT 222
            :|.|...|.|..      .||.|...:.|          ....|..||.:...       |:.|:
Human    14 KAGESLEPAYYD------CRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF-------HHGTS 65

  Fly   223 ASALLAPLHSLTSLQLTQQQQRFLG--KTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNA 285
            ..:......:..||.......:|.|  ..|:|.|..|....:.......::.|:.: ...|||:.
Human    66 GISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTN-SSEGQGHL 129

  Fly   286 SAGSNGKRKRSW----------SRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVK 340
            :..|:......|          .|..:|..|...||.:|....|:|:..|.:::..|.||:.|||
Human   130 NQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVK 194

  Fly   341 VWFQNRRMKWRHTRENLKSGQEKQPSA-----VPESG 372
            :|||||||||:  :||.|   :|.|.|     |.|.|
Human   195 IWFQNRRMKWK--KENNK---DKLPGARDEEKVEEEG 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	23/52 (44%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		6/40 (15%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeobox	153..205	CDD:306543	23/51 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910