Protein Alignment H2.0 and HOXB5

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 63/282 - (22%)
• Similarity: 99/282 - (35%)
• Gaps: 97/282 - (34%)

  Fly   132 PTFTPTSSHTYPFVGLD--------------------KLFPGPYMDYKSVLRPTPIRAAEHAAPT 176
            |....|.|:.|.:.|:|                    :.||.|..:      |...:||...:.:
Human    37 PAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQE------PRFRQAASSCSLS 95

  Fly   177 YPTL--ATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLT 239
            .|..  .||.                 ..|..|   .....|...:|:||         :|...|
Human    96 SPESLPCTNG-----------------DSHGAK---PSASSPSDQATSAS---------SSANFT 131

  Fly   240 QQQQRFLGKTPQQLL------DIAPTSPAAAAAATSQNGAHGHGGGNGQ-------------GNA 285
            :..:......|::..      .:|...|...|.:|:        ...||             .:.
Human   132 EIDEASASSEPEEAASQLSSPSLARAQPEPMATSTA--------APEGQTPQIFPWMRKLHISHD 188

  Fly   286 SAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKW 350
            ..|.:|||    :|..::..|...||.:|...:|:|:..|.::|..|.|::.|:|:|||||||||
Human   189 MTGPDGKR----ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 249

  Fly   351 RHTREN-LKS------GQEKQP 365
            :  ::| |||      |...||
Human   250 K--KDNKLKSMSLATAGSAFQP 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/52 (40%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	22/146 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		22/138 (16%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeobox	198..251	CDD:395001	22/54 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910