DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and HOXA10

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_061824.3	Gene:	HOXA10 / 3206	HGNCID:	5100	Length:	410	Species:	Homo sapiens

Alignment Length:	159	Identity:	40/159 - (25%)
Similarity:	67/159 - (42%)	Gaps:	51/159 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 PPP----------------HNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAA 263
            |||                |.|::|:..|:|                              :|:.
Human   274 PPPTLACGSGGGSQGDEEAHASSSAAEELSP------------------------------APSE 308

  Fly   264 AAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKL 328
            ::.|:.:..:.|:..|....|.....:|::|    |..::..|...||.:|....|:|:..|.::
Human   309 SSKASPEKDSLGNSKGENAANWLTAKSGRKK----RCPYTKHQTLELEKEFLFNMYLTRERRLEI 369

  Fly   329 AARLNLTDAQVKVWFQNRRMKWRH-TREN 356
            :..::|||.|||:||||||||.:. .|||
Human   370 SRSVHLTDRQVKIWFQNRRMKLKKMNREN 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	22/52 (42%)
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..158
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..339		14/94 (15%)
		Homeobox	339..392	CDD:278475	23/56 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910