Protein Alignment H2.0 and HLX

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 113/318 - (35%)
• Similarity: 144/318 - (45%)
• Gaps: 83/318 - (26%)

  Fly   159 KSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPP------- 216
            :|.|||||:.|.......:|...:.....:|.|..||.||    |..|:   ||..||
Human    90 RSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQ----QQQPQ---QQQPPPPPRAGAL 147

  Fly   217 ------------PHNSTTA----------------SALLAP-------LHSLTSLQLTQQQQ--- 243
                        ||:|.:|                ||...|       |..|||| ||..:.
Human   148 QPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSL-LTGGRPAGV 211

  Fly   244 RFLGKTP---QQLLDIAPTSPAAAAA----ATSQNGAHGHGGGNGQG------NASAGSNGKRKR 295
            ...|..|   |....:.|.:.|:|..    :..:|...........|      ..:.....||||
Human   212 HLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKR 276

  Fly   296 SWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRE-NLKS 359
            ||||||||||||||||.:|:.|||:|||||::|||.|.|||||||||||||||||||::| ..:.
Human   277 SWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQK 341

  Fly   360 GQEKQPSAVPESGGVFKTSTPSGDG-----TPQ----EALDYSSDSCSSVDLSEQADE 408
            .::|:....| |||     .|:.||     :|.    ||...|||| .|:|::....|
Human   342 DKDKEAGEKP-SGG-----APAADGEQDERSPSRSEGEAESESSDS-ESLDMAPSDTE 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	43/52 (83%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		16/61 (26%)
		Abdominal-A	227..>344	CDD:332641	58/116 (50%)
		Homeobox	279..332	CDD:306543	43/52 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		22/69 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159260
Domainoid	1	1.000	99	1.000	Domainoid score	I7116
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4719
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009017
OrthoInspector	1	1.000	-	-		oto89889
orthoMCL	1	0.900	-	-		OOG6_110467
Panther	1	1.100	-	-	LDO	PTHR46808
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.750