DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and emx3

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_571354.1	Gene:	emx3 / 30536	ZFINID:	ZDB-GENE-990415-53	Length:	233	Species:	Danio rerio

Alignment Length:	245	Identity:	66/245 - (26%)
Similarity:	98/245 - (40%)	Gaps:	53/245 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 LRPTPIRAAE--HAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTAS 224
            :|||.:|..|  |.:|.....              |:.....:...|:.:...    |...:|.|
Zfish    30 IRPTALRFTESIHPSPFGSCF--------------QNSGRTLYSSSPEMMFTD----PSTHSTNS 76

  Fly   225 ALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGS 289
            .|     ||..||:..|.  |.....:..|:..|.        ..:|...||   ..||:.|:..
Zfish    77 GL-----SLRHLQIPTQP--FFSPHQRDTLNFYPW--------VLRNRYLGH---RFQGDDSSPE 123

  Fly   290 N------GKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRM 348
            |      ..||....|..||..|...||..|::..|:...:|::||..|.||:.||||||||||.
Zfish   124 NLLLHGPFSRKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANGLCLTETQVKVWFQNRRT 188

  Fly   349 KWRHTRENLKSGQEKQPSAVPESGG---VFKTSTPSGDGTPQEALDYSSD 395
            |  |.|:.|   :|:.|....:..|   |.:....:..|:|:: :|..|:
Zfish   189 K--HKRQKL---EEESPDPQQKRKGSQHVSRWRVATQQGSPED-IDVISE 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	25/52 (48%)
emx3	NP_571354.1	Homeobox	139..191	CDD:278475	25/53 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910