DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and rx3

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_571302.1	Gene:	rx3 / 30474	ZFINID:	ZDB-GENE-990415-238	Length:	292	Species:	Danio rerio

Alignment Length:	110	Identity:	39/110 - (35%)
Similarity:	55/110 - (50%)	Gaps:	10/110 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 GNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRR 347
            |..|...|.|:|...:|..|:..|...||..|::..|.....|.:||.::||.:.:|:|||||||
Zfish    94 GKLSDDENPKKKHRRNRTTFTTFQLHELERAFEKSHYPDVYSREELALKVNLPEVRVQVWFQNRR 158

  Fly   348 MKWRHTRENLKSG----QEKQPSAVPESGGVFKTSTPSGDGTPQE 388
            .|||. :|.|:..    ||....::|.||.:     ..|.|.|.|
Zfish   159 AKWRR-QEKLEVSSIKLQESSMLSIPRSGPL-----SLGSGLPLE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/52 (40%)
rx3	NP_571302.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		Octapeptide motif	32..39
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..72
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	85..107		5/12 (42%)
		Homeobox	110..162	CDD:278475	21/51 (41%)
		OAR	268..284	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	272..285
		Nuclear localization signal. /evidence=ECO:0000255	278..282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910