DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and rx1

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_571300.2	Gene:	rx1 / 30472	ZFINID:	ZDB-GENE-990415-236	Length:	330	Species:	Danio rerio

Alignment Length:	202	Identity:	48/202 - (23%)
Similarity:	76/202 - (37%)	Gaps:	42/202 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 PKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQ 270
            |..|.|:.:|..|        |.||...:..........|..|....|.|:.....:.:.:..|.
Zfish    72 PGKLDQRVQPYGH--------LPPLRDGSEQPTFHDADMFSNKCDGDLGDLRKAIESDSKSPDSA 128

  Fly   271 NGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLT 335
            :                |...|:|...:|..|:..|...||..|::..|.....|.:||.::||.
Zfish   129 D----------------GEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLP 177

  Fly   336 DAQVKVWFQNRRMKWRHTRENLKSGQEK----------QPSAVPESGGVFKT-------STPSGD 383
            :.:|:|||||||.|||. :|.:.:...|          :||..|..|.:..:       .:|...
Zfish   178 EVRVQVWFQNRRAKWRR-QEKIDASTMKLHDSPMLSFNRPSMHPTVGPMNNSLPLDPWLPSPLSS 241

  Fly   384 GTPQEAL 390
            .||..::
Zfish   242 ATPVHSI 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/52 (40%)
rx1	NP_571300.2	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..104		8/39 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..142		4/39 (10%)
		Homeobox	141..193	CDD:278475	21/51 (41%)
		OAR	302..318	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
		Nuclear localization signal. /evidence=ECO:0000255	312..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910