DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Dlx4

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001100510.1	Gene:	Dlx4 / 303469	RGDID:	1308744	Length:	238	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	61/257 - (23%)
Similarity:	89/257 - (34%)	Gaps:	94/257 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 GHATLPP-TFTPTSSHTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFH 189
            |.|..|. :|:.|..|.     |...:|||.....|.|.    ...:.|||:.|         ||
  Rat    38 GTAASPDLSFSQTYGHL-----LSYSYPGPATPGDSYLS----SQQQSAAPSRP---------FH 84

  Fly   190 QHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLL 254
            |..:           ||:.|..:           |..||                         |
  Rat    85 QPTE-----------HPQELEAE-----------SEKLA-------------------------L 102

  Fly   255 DIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKY 319
            .:.|:.|:..                            ||....|.::|:||.:.|..:||..:|
  Rat   103 SLEPSQPSLT----------------------------RKLRKPRTIYSSLQLQHLNQRFQHTQY 139

  Fly   320 ITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTPS 381
            :..|:|.:|||:|.||..|||:||||:|.|::...:......|:..|..|.|......:.||
  Rat   140 LALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQSSGELEEDFSGRPPSLSPHSLTLPS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	25/52 (48%)
Dlx4	NP_001100510.1	Homeobox	118..172	CDD:395001	25/53 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910