Protein Alignment H2.0 and TLX3

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 81/335 - (24%)
• Similarity: 115/335 - (34%)
• Gaps: 128/335 - (38%)

  Fly    60 SPTSA-TSTTKVKLSFSVDRLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANAESR 123
            :|.|| |......:||.:|::|.| |::....:...|...|...|
Human     3 APASAQTPHPHEPISFGIDQILNS-PDQDSAPAPRGPDGASYLGG-------------------- 46

  Fly   124 RFGHATLPPTFTPTSSHTYP-----FVGLDKLFPGPYMDYKS-----------VLR--------- 163
                   ||...|.:  |||     |.||.    .|:.|..|           |:|
Human    47 -------PPGGRPGA--TYPSLPASFAGLG----APFEDAGSYSVNLSLAPAGVIRVPAHRPLPG 98

  Fly   164 --PTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASAL 226
              |.|:.:|..|.|:.||:::...|.|...:..:..                   ..:..||:|.
Human    99 AVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRF-------------------VKDRFTAAAA 144

  Fly   227 LAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNG 291
            |.|. ::|         |.:|...|.     .|.|
Human   145 LTPF-TVT---------RRIGHPYQN-----RTPP------------------------------ 164

  Fly   292 KRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTREN 356
            |||:  .|..||.:|...||.:|.:|||:...:|..||..|.:||||||.||||||.|||.....
Human   165 KRKK--PRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAE 227

  Fly   357 LKSGQEKQPS 366
            .:..:.:|.|
Human   228 EREAERQQAS 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/52 (52%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		16/82 (20%)
		Homeobox	169..223	CDD:395001	28/53 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810