DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment H2.0 and tlx1

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_739571.1	Gene:	tlx1 / 266964	ZFINID:	ZDB-GENE-021021-2	Length:	301	Species:	Danio rerio

Alignment Length:	165	Identity:	45/165 - (27%)
Similarity:	70/165 - (42%)	Gaps:	27/165 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 HKP--PPHNSTTASALLAP-------LHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAAT 268
            |:|  ..|:|...||...|       :::||.|.....:........:..:.::|.:........
Zfish   103 HRPLGSVHSSIPTSAATVPSMGSMGTINNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHP 167

  Fly   269 SQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLN 333
            .||                .:..|:|:  .|..|:.||...||.:|.:|||:...:|..||..|.
Zfish   168 YQN----------------RTPPKKKK--PRTSFTRLQICELEKRFHRQKYLASAERAALAKALK 214

  Fly   334 LTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAV 368
            :||||||.||||||.|||......:..:.:|.:.:
Zfish   215 MTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/52 (52%)
tlx1	NP_739571.1	Homeobox	179..232	CDD:278475	27/52 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810