Protein Alignment H2.0 and ALX3

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 78/295 - (26%)
• Similarity: 98/295 - (33%)
• Gaps: 105/295 - (35%)

  Fly   140 HTYPF-VGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQ 203
            |..|| ||   ..||||:  .|...|...:....|||
Human     5 HCAPFRVG---PAPGPYV--ASGDEPPGPQGTPAAAP---------------------------- 36

  Fly   204 HHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFL---GKTPQQLL-DIAP------ 258
                |||.  .||.....|......||            :.:|   .|.|.:.| |:.|
Human    37 ----HLHP--APPRGPRLTRFPACGPL------------EPYLPEPAKPPAKYLQDLGPGPALNG 83

  Fly   259 ----TSPAAAAAATSQ-----------NGAHGHGGGNGQGN-----------ASAG-------SN 290
                ..||.|...||:           .|....|..|.||:           .|.|       :.
Human    84 GHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAK 148

  Fly   291 GKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLTDAQVKVWFQNRRMKWRH 352
            .|.|:..:|..||..|.:.||..||:..|   ||   |.:||.|.:||:|:|:|||||||.|||.
Human   149 NKSKKRRNRTTFSTFQLEELEKVFQKTHY---PDVYAREQLALRTDLTEARVQVWFQNRRAKWRK 210

  Fly   353 TRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTPQ 387
            .....|..:.:.|........|.    |..|..||
Human   211 RERYGKIQEGRNPFTAAYDISVL----PRTDSHPQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/55 (49%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		33/149 (22%)
		PRK12323	<13..131	CDD:237057	33/165 (20%)
		Homeobox	157..210	CDD:365835	28/55 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910