DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Otx1

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_037241.1	Gene:	Otx1 / 25646	RGDID:	3237	Length:	355	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	47/142 - (33%)
Similarity:	67/142 - (47%)	Gaps:	31/142 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 GGNGQGNASAGSN----------GKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLA 329
            |.||.|.|....:          ..||:...|..|:..|...||..|.:.:|   ||   |.::|
  Rat    11 GMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRY---PDIFMREEVA 72

  Fly   330 ARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQ-------EKQPSAVPESGGVFKTSTPSGDGTPQ 387
            .::||.:::|:|||:|||.|   .|:..:||.       :|:.|.|.||.|    |..||..||
  Rat    73 LKINLPESRVQVWFKNRRAK---CRQQQQSGNGTKSRPVKKKSSPVRESSG----SESSGQFTP- 129

  Fly   388 EALDYSSDSCSS 399
            .|:..|:.|.||
  Rat   130 PAVSSSASSSSS 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/55 (38%)
Otx1	NP_037241.1	Homeobox	42..94	CDD:278475	21/57 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..144		20/58 (34%)
		TF_Otx	178..274	CDD:281521
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910