DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Drgx

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_665710.2	Gene:	Drgx / 252880	RGDID:	628616	Length:	263	Species:	Rattus norvegicus

Alignment Length:	124	Identity:	51/124 - (41%)
Similarity:	67/124 - (54%)	Gaps:	21/124 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 GNASAG--SNG--KRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLTDAQVK 340
            ||.|.|  .:|  :||:..:|..|:..|.:.||..|.|..|   ||   |.:||.::|||:|:|:
  Rat    17 GNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHY---PDVFTREELAMKINLTEARVQ 78

  Fly   341 VWFQNRRMKWRHTRENLKSGQE---KQPSA---VPESGGVFKTSTPSGDGT--PQEALD 391
            |||||||.|||.| |...|.||   |:|.|   .|....:  .|.|.||..  .:|||:
  Rat    79 VWFQNRRAKWRKT-ERGASDQEPGAKEPMAEVTPPPVRNI--NSPPPGDQARGKKEALE 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	26/55 (47%)
Drgx	NP_665710.2	Homeobox	37..90	CDD:395001	27/55 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..135		18/50 (36%)
		OAR	201..218	CDD:397759
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	204..217
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..263
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910