Protein Alignment H2.0 and Tlx2

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 289
• Identity: 74/289 - (25%)
• Similarity: 100/289 - (34%)
• Gaps: 99/289 - (34%)

  Fly   200 HHHQHHP------KHLHQQHKPP-----------PHNSTTA-------SALLAPLHSLTSLQLTQ 240
            ||..||.      ..:....:||           .|..:.|       ::..||..||.||
Mouse     9 HHLPHHEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGFHGASGYAPAGSLASL---- 69

  Fly   241 QQQRFLGKTP--------QQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAG------SNG 291
              .|..|..|        .:.|.:.|.|.||.|..    |..|.||..|    .||      .:|
Mouse    70 --PRGSGVGPGGVIRVPAHRPLPVPPPSGAAPAVP----GPSGLGGAGG----LAGLTFPWMDSG 124

  Fly   292 KR-----------------------------KRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRK 327
            :|                             ||...|..||..|...||.:|.:|||:...:|..
Mouse   125 RRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAA 189

  Fly   328 LAARLNLTDAQVKVWFQNRRMKW-RHTRENLKSGQEK--------QPSAVPESGGVFKTSTPSGD 383
            ||..|.:||||||.||||||.|| |.|.|..::.:.:        |..|:|.         |...
Mouse   190 LAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPR---------PLRP 245

  Fly   384 GTPQEALDYSSDSCSSVDLSEQADEDDNI 412
            ..|.:.|...:.|..::...:...||:.:
Mouse   246 PLPPDPLCLHNSSLFALQNLQPWAEDNKV 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	28/53 (53%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		4/31 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		6/29 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		4/25 (16%)
		Homeobox	160..213	CDD:306543	27/52 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810