Protein Alignment H2.0 and Pax4

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_035168.1
• Gene: Pax4 / 18506
• MGIID: 97488
• Length: 349
• Species: Mus musculus
• Alignment Length: 279
• Identity: 76/279 - (27%)
• Similarity: 115/279 - (41%)
• Gaps: 64/279 - (22%)

  Fly   153 GPYMDYKS-VLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQ----HHHHQHHPKHLHQQ 212
            |.|  |:: ||.|..|..::      |.|||.|::......|.::..    ...||...:.|..|
Mouse    59 GRY--YRTGVLEPKCIGGSK------PRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQ 115

  Fly   213 HKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHG 277
            .|.|  :.::.:.:|..|....||..||.      ::|..|   ||..|:..:...:..|.|
Mouse   116 DKAP--SVSSINRVLRALQEDQSLHWTQL------RSPAVL---APVLPSPHSNCGAPRGPH--- 166

  Fly   278 GGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVW 342
                     .|::.:     :|.:||..|.:.||.:||:.:|.....|.||||..:|.:..|:||
Mouse   167 ---------PGTSHR-----NRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVW 217

  Fly   343 FQNRRMKWRHTRENLKSGQEKQPSA-----VPESGGVFKTSTPSGDGTPQEALDY---------- 392
            |.|||.|||. :|.|| .:.:.|.|     ||::.....::..|....|..||..
Mouse   218 FSNRRAKWRR-QEKLK-WEAQLPGASQDLTVPKNSPGIISAQQSPGSVPSAALPVLEPLSPSFCQ 280

  Fly   393 -----SSDSCSSVDLSEQA 406
                 :...||| |.|.||
Mouse   281 LCCGTAPGRCSS-DTSSQA 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	23/52 (44%)
Pax4	NP_035168.1	PAX	5..129	CDD:128645	19/79 (24%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		3/6 (50%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		9/49 (18%)
		Homeobox	174..226	CDD:278475	23/51 (45%)
		Transcription repression	278..349		7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910