DRSC/TRiP Functional Genomics Resources

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Protein Alignment H2.0 and ttx-3

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001257168.1 Gene:ttx-3 / 181357 WormBaseID:WBGene00006654 Length:409 Species:Caenorhabditis elegans


Alignment Length:469 Identity:95/469 - (20%)
Similarity:134/469 - (28%) Gaps:196/469 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 SMPENLSTHMYGECEVNPTLAKCPDPVNVDHELPTKE---------SCASTTIVSTSPTSATSTT 68
            |..|.::||:        .....|.....|.....||         |...|.:.|.||:|:|.:.
 Worm    34 SSKETIATHV--------VTNSVPSAFQFDWSSHFKEEYDLVEKLNSPQYTNLTSISPSSSTDSN 90

  Fly    69 KVKL-SFSVDRLLGSEPEESHRQSSSSPSTKSCC--------------DG-----SILAC--CSF 111
            .:.| ...:.::   ||          .....||              ||     :.|.|  |..
 Worm    91 NLILRQIQIPKI---EP----------ALLNQCCLCTFAIVDKEISVVDGKYYHNNCLRCQMCDI 142

  Fly   112 PHCFSQ------------------------------------ANAESRRFGHATLPPTFTPTSSH 140
            |..:|.                                    ..|:...|.||..          
 Worm   143 PFEYSDKCYVRDGVFLCRADHAKRYQKCCRKCEIPLNREDMVMKAKEMIFHHACF---------- 197

  Fly   141 TYPFVGLDKLFPGPYMD-----------YKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQ 194
             ..|:...||.||.|..           :.:.:|.| :...|.|..|.|.:..            
 Worm   198 -VCFICGIKLNPGDYYTMSPQGHLYCHAHYNAVRST-VLCEEAAVATVPAVVA------------ 248

  Fly   195 QHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPT 259
                              ..|||..:|||....||          :|..|              .
 Worm   249 ------------------PPPPPPTTTTAPPPAAP----------EQPPR--------------E 271

  Fly   260 SPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD 324
            :...|.|:|.::           ||.|.....||.|:    .|.:.|.:.::..|.........|
 Worm   272 ASTEAEASTDED-----------GNGSGSQRSKRMRT----SFKHHQLRAMKTYFALNHNPDAKD 321

  Fly   325 RRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTP--SGDGTPQ 387
            .::|||:.|||...::|||||.|.|:|  ||....|:...|..|         |.|  |.|..|.
 Worm   322 LKQLAAKTNLTKRVLQVWFQNARAKYR--RELHDGGRSSSPLCV---------SAPLASMDMNPP 375

  Fly   388 EALDYSSDSCSSVD 401
            .:   ||.|..|.|
 Worm   376 LS---SSSSGHSTD 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 17/52 (33%)
ttx-3NP_001257168.1 LIM 110..163 CDD:259829 9/52 (17%)
LIM 171..226 CDD:295319 10/65 (15%)
Homeobox 296..348 CDD:278475 18/55 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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