DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and ceh-14

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_509273.1	Gene:	ceh-14 / 181012	WormBaseID:	WBGene00000438	Length:	351	Species:	Caenorhabditis elegans

Alignment Length:	133	Identity:	37/133 - (27%)
Similarity:	57/133 - (42%)	Gaps:	31/133 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 GSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLTDAQVKVWFQNRRMK 349
            ||| ||.|       :.:..|.||...|..:..:||.   |.:||:...|....|:|||||||.|
Worm   178 GSN-KRPR-------TTISAKSLETLKQAYQTSSKPARHVREQLASETGLDMRVVQVWFQNRRAK 234

  Fly   350 WRHTRENLKSGQEKQPSAVPESGGVFKTS--TPSGDGTPQEALDYSSDSCSSVDLSEQADEDDNI 412
            .:..::              ::|..:|:|  ..|...:|.|:::..|.:...:|    ...||..
Worm   235 EKRLKK--------------DAGRRWKSSNRAESDSNSPIESINGQSPNYLYLD----HPMDDGN 281

  Fly   413 EIN 415
            |.|
Worm   282 ESN 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	19/55 (35%)
ceh-14	NP_509273.1	LIM	48..103	CDD:278823
		LIM2_Lhx3_Lhx4	107..163	CDD:188762
		COG5576	<172..295	CDD:227863	37/133 (28%)
		Homeobox	183..236	CDD:278475	20/59 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910