DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and ceh-24

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_506419.3	Gene:	ceh-24 / 179877	WormBaseID:	WBGene00000447	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	62/235 - (26%)
Similarity:	91/235 - (38%)	Gaps:	78/235 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 TASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNAS 286
            :.:::|:||.||..:|             ||||.:|.:............||..:|.|...||..
Worm    47 SVNSILSPLESLVRVQ-------------QQLLKMAASKSGTPGTNAGVPGAFPYGPGRLPGNYF 98

  Fly   287 AGS------------NG----------------------------------KRKRSWSRAVFSNL 305
            ||.            ||                                  :|||   |.:||..
Worm    99 AGPFPGYSGAQPNWYNGNDPRFAAAAALLPCSIDPVRSAINHQFSMSSMSQRRKR---RVLFSQA 160

  Fly   306 QRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPE 370
            |...||.:|:|.||:|.|:|.:||..:.||..|||:||||.|.|.:.        |||: .|:..
Worm   161 QVYELERRFKQAKYLTAPEREQLANSIRLTPTQVKIWFQNHRYKCKR--------QEKE-KAMSG 216

  Fly   371 SGGVFKTSTPSGDGTPQEALDYSSDSCSSVDLSEQADEDD 410
            .|.....|:|..|..       ..|...|:::.::.||::
Worm   217 LGHSEDGSSPPPDND-------DDDDKYSIEMDDKDDEEE 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	26/52 (50%)
ceh-24	NP_506419.3	Homeobox	153..206	CDD:278475	27/55 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910