Protein Alignment H2.0 and DLX2

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_004396.1
• Gene: DLX2 / 1746
• HGNCID: 2915
• Length: 328
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 69/263 - (26%)
• Similarity: 97/263 - (36%)
• Gaps: 103/263 - (39%)

  Fly   200 HHHQHHPKHLHQQHKPPPH--------NSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDI 256
            |..|......:.||:.||.        ||:::|:|..|..|
Human    13 HSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHKPQES------------------------ 53

  Fly   257 APTSPAAAAAATS--QNGAHGHGGGNGQGN--ASAGS---------------------------- 289
             ||.|.:.|..:|  .|..|..|||.|.|:  |..||
Human    54 -PTLPVSTATDSSYYTNQQHPAGGGGGGGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGYTAAYT 117

  Fly   290 ----------------------------NGKRKR-SWSRAVFSNLQRKGLEIQFQQQKYITKPDR 325
                                        |||.|: ...|.::|:.|...|:.:||:.:|:..|:|
Human   118 SYAPYGTSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPER 182

  Fly   326 RKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQ---EKQP--SAVPESGGVFKTSTPSGD-G 384
            .:|||.|.||..|||:||||||.|:   ::..|||:   |:.|  ||.|.......::..|.| |
Human   183 AELAASLGLTQTQVKIWFQNRRSKF---KKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFG 244

  Fly   385 TPQ 387
            .||
Human   245 VPQ 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	25/52 (48%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..81		22/89 (25%)
		DLL_N	51..132	CDD:289198	16/105 (15%)
		Homeobox	155..208	CDD:278475	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..270		13/37 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910