Protein Alignment H2.0 and GSX2

DIOPT Version :9

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 65/229 - (28%)
• Similarity: 93/229 - (40%)
• Gaps: 65/229 - (28%)

  Fly   200 HHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAA 264
            |||.|.|:|.|..|:|....|..|:|..|...:..:.         ||.         |...|..
Human   126 HHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAA---------LGH---------PQHHAPV 172

  Fly   265 AAATSQNGA---HGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRR 326
            ..||:.|.|   ..|....|..:||...||||.|:    .|::.|...||.:|....|:::..|.
Human   173 CTATTYNVADPRRFHCLTMGGSDASQVPNGKRMRT----AFTSTQLLELEREFSSNMYLSRLRRI 233

  Fly   327 KLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTPQEALD 391
            ::|..|||::.|||:||||||:|  |.:|                          |.||.:.:
Human   234 EIATYLNLSEKQVKIWFQNRRVK--HKKE--------------------------GKGTQRNS-- 268

  Fly   392 YSSDSC--SSVDLSEQADED--------DNIEIN 415
            ::...|  |.|..:...|||        |:.||:
Human   269 HAGCKCVGSQVHYARSEDEDSLSPASANDDKEIS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/52 (40%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		11/24 (46%)
		Homeobox	206..258	CDD:306543	22/57 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910