DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Lhx3

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001034742.1	Gene:	Lhx3 / 16871	MGIID:	102673	Length:	402	Species:	Mus musculus

Alignment Length:	133	Identity:	36/133 - (27%)
Similarity:	49/133 - (36%)	Gaps:	35/133 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 AGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD-----RRKLAARLNLTDAQVKVWFQNR 346
            |.:..||.|       :.:..|.||.  .:..|.|.|.     |.:|::...|....|:||||||
Mouse   158 AEATAKRPR-------TTITAKQLET--LKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNR 213

  Fly   347 RMK------------W-------RHTRENLKSGQEKQPSAVPESGGVFKTSTPS-GDGTPQEALD 391
            |.|            |       :.:|.:.||.::...........|..|..|| .|..|...|
Mouse   214 RAKEKRLKKDAGRQRWGQYFRNMKRSRGSSKSDKDSIQEGQDSDAEVSFTDEPSMADMGPANGL- 277

  Fly   392 YSS 394
            |||
Mouse   278 YSS 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	19/76 (25%)
Lhx3	NP_001034742.1	LIM1_Lhx3b	33..87	CDD:188851
		LIM2_Lhx3_Lhx4	95..150	CDD:188762
		Homeobox	165..218	CDD:278475	19/61 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910