Protein Alignment H2.0 and NKX6-3

DIOPT Version :10

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 60/198 - (30%)
• Similarity: 78/198 - (39%)
• Gaps: 59/198 - (29%)

  Fly   249 TPQQLLDIAPTSPAAAAAATSQNG---AHGHGGGNGQ--------GNASAGSN------------ 290
            ||..:.||. :.|.||...:..:|   ..|.||.:.|        ||.|...|
Human    51 TPHGITDIL-SRPVAAPNNSLLSGYPHVAGFGGLSSQGVYYSPQVGNFSKAGNEYPTRTRNCWAD 114

  Fly   291 -------GKR-------------KRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLT 335
                   |::             |:..:|..|:..|...||..|:|.||:..|:|.:||..|.:|
Human   115 TGQDWRGGRQCSNTPDPLSDSIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMT 179

  Fly   336 DAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTPQE--------ALDY 392
            ::||||||||||.|||.     ||..|...|.....||.  .:...||..|.|        .||.
Human   180 ESQVKVWFQNRRTKWRK-----KSALEPSSSTPRAPGGA--GAGAGGDRAPSENEDDEYNKPLDP 237

  Fly   393 SSD 395
            .||
Human   238 DSD 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	28/72 (39%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	28/57 (49%)