DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Mnx1

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_064328.2	Gene:	Mnx1 / 15285	MGIID:	109160	Length:	404	Species:	Mus musculus

Alignment Length:	268	Identity:	75/268 - (27%)
Similarity:	102/268 - (38%)	Gaps:	66/268 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 HHHQH-----------------------HP------KHLHQQ-----HKPPPHNSTTASALLAPL 230
            |||.|                       ||      ..|..|     |....:::..|:|.||..
Mouse   114 HHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYSYSAAAAAAALAGQ 178

  Fly   231 HSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNG-------QGNASAG 288
            |...|....|.|    |..|..     |..|....|:|.|..........|       ..::.|.
Mouse   179 HPALSYSYPQVQ----GAHPAH-----PADPIKLGASTFQLDQWLRASTAGMILPKMPDFSSQAQ 234

  Fly   289 SN--GKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWR 351
            ||  ||.:|  .|..|::.|...||.||:..||:::|.|.::|..|.||:.|||:|||||||||:
Mouse   235 SNLLGKCRR--PRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWK 297

  Fly   352 HTRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTPQEAL---DYSSDSCSS------VDLSEQAD 407
            .::   |:.::....|..:.||...|.....:...:|.|   ..|.|..|.      .|.....|
Mouse   298 RSK---KAKEQAAQEAEKQKGGGGGTGKGGSEEKTEEELMGPPVSGDKASGRRLRDLRDSDPDED 359

  Fly   408 EDDNIEIN 415
            |||..|.|
Mouse   360 EDDEEEDN 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	26/52 (50%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..80
		Homeobox	244..297	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..404		17/72 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910