DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment H2.0 and Hlx

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_032276.1 Gene:Hlx / 15284 MGIID:96109 Length:476 Species:Mus musculus


Alignment Length:305 Identity:113/305 - (37%)
Similarity:139/305 - (45%) Gaps:60/305 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   159 KSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQ---HQQHHHHQHHPKHLHQQHKPP---- 216
            :|.|||||:.|.......:|...:.....||||..||   .||....|..|.......:||    
Mouse    89 RSPLRPTPVVAPSEVPAGFPQRLSPLSAAFHQHLPQQSPTQQQQPQQQPPPPPRAVSLQPPTSGT 153

  Fly   217 ---PHNSTTA----------------SALLAP-------LHSLTSLQLTQQQQ---RFLGKTP-- 250
               ||:|.:|                ||...|       |..|||| ||..:.   ...|..|  
Mouse   154 RVVPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSL-LTGGRPAGVHLAGLQPSA 217

  Fly   251 -QQLLDIAPTSPAAA----AAATSQNGAHGHGGGNGQG------NASAGSNGKRKRSWSRAVFSN 304
             |....:.|.|.|:|    .::..:|...........|      ..:.....|||||||||||||
Mouse   218 GQFFASLDPISEASAILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSN 282

  Fly   305 LQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRE------NLKSGQEK 363
            |||||||.:|:.|||:|||||::|||.|.|||||||||||||||||||::|      ..|...||
Mouse   283 LQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEK 347

  Fly   364 QPSAVPESGGVFKTSTPSGDGTPQEALDYSSDSCSSVDLSEQADE 408
            ....||..|...:.|....:|   ||...|||| .|:|::....|
Mouse   348 PSGGVPAEGEREERSPSRSEG---EAESESSDS-ESLDMAPSDTE 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 43/52 (83%)
HlxNP_032276.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 120..169 14/48 (29%)
COG5576 224..>341 CDD:227863 59/116 (51%)
Homeobox 276..329 CDD:278475 43/52 (83%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 328..401 21/65 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 413..476
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167849629
Domainoid 1 1.000 99 1.000 Domainoid score I7129
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 129 1.000 Inparanoid score I4641
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0009017
OrthoInspector 1 1.000 - - oto93465
orthoMCL 1 0.900 - - OOG6_110467
Panther 1 1.100 - - LDO PTHR46808
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R7075
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1312.780

Return to query results.
Submit another query.