DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and dmbx1a

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_694509.1	Gene:	dmbx1a / 142987	ZFINID:	ZDB-GENE-020117-1	Length:	388	Species:	Danio rerio

Alignment Length:	257	Identity:	65/257 - (25%)
Similarity:	94/257 - (36%)	Gaps:	91/257 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 NALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLG 247
            :|:...||...||      .||.|     .::|..|..|.|                   :|..|
Zfish    18 SAMYNLHQQAAQQ------AQHAP-----DYRPSVHALTLA-------------------ERLAG 52

  Fly   248 KTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEI 312
            .|.|.::        ..|...||:                     ||:..||..|:..|.:.||.
Zfish    53 CTFQDII--------LEARYGSQH---------------------RKQRRSRTAFTAQQLEALEK 88

  Fly   313 QFQQQKYITKPD---RRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGV 374
            .||:..|   ||   |.:||...||.:|:|:|||:|||.|:|..:.:|:..|.::...|...|.:
Zfish    89 TFQKTHY---PDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDVSTDGAL 150

  Fly   375 F-----------------KTSTPSGDGTPQEALDYSSDSCSSVDL---------SEQADEDD 410
            .                 .:||.|......||..::..|..||:|         ||.|.||:
Zfish   151 AASDKDEAPSTLNLENQPPSSTSSSSSMEAEAAPHALGSELSVELNVTSAEQSGSESATEDN 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	25/55 (45%)
dmbx1a	NP_694509.1	Homeobox	74..127	CDD:278475	25/55 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..272		18/84 (21%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	365..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910