DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and Dlx3

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_034185.1	Gene:	Dlx3 / 13393	MGIID:	94903	Length:	287	Species:	Mus musculus

Alignment Length:	120	Identity:	43/120 - (35%)
Similarity:	65/120 - (54%)	Gaps:	18/120 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 NGKRKR-SWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHT 353
            |||.|: ...|.::|:.|...|:.:||:.:|:..|:|.:|||:|.||..|||:||||||.|::..
Mouse   123 NGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKL 187

  Fly   354 RENLKSGQEKQPS-------AVPESGGVFKTSTPSGDGTPQEA-------LDYSS 394
            .:|.:...|..|:       ..|.|..::.||:.|   ||..|       |.||:
Mouse   188 YKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHS---TPAPARNPLPPPLPYSA 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	25/52 (48%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:315147
		Abdominal-A	<109..224	CDD:332641	37/103 (36%)
		Interaction with DNA. /evidence=ECO:0000250\|UniProtKB:O60479	131..181		22/49 (45%)
		Homeobox	132..185	CDD:306543	25/52 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..287		13/48 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910