Protein Alignment H2.0 and Dlx2

DIOPT Version :10

• Sequence 1: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 251
• Identity: 66/251 - (26%)
• Similarity: 98/251 - (39%)
• Gaps: 97/251 - (38%)

  Fly   210 HQQHKPP------PHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAAT 268
            ||..:||      |..::.:|:..:.||.                 ||:    :||.|.:.|..:
Mouse    24 HQHQQPPSGAGAGPGGNSNSSSSNSSLHK-----------------PQE----SPTLPVSTATDS 67

  Fly   269 S-----QNGAHGHGGG--------------NGQGNASAGS------------------------- 289
            |     |:.|.|.|||              :|..|.|..:
Mouse    68 SYYTNQQHPAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYTSYAPYGTSSSPV 132

  Fly   290 ----------------NGKRKR-SWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDA 337
                            |||.|: ...|.::|:.|...|:.:||:.:|:..|:|.:|||.|.||..
Mouse   133 NNEPDKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQT 197

  Fly   338 QVKVWFQNRRMKWRHTRENLKSGQ---EKQP--SAVPESGGVFKTSTPSGD-GTPQ 387
            |||:||||||.|:   ::..|||:   |:.|  ||.|.......::..|.| |.||
Mouse   198 QVKIWFQNRRSKF---KKMWKSGEIPTEQHPGASASPPCASPPVSAPASWDFGAPQ 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	27/60 (45%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		19/79 (24%)
		DLL_N	54..135	CDD:463567	15/84 (18%)
		Homeodomain	156..212	CDD:459649	25/58 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		10/32 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332