DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and AgaP_AGAP000063

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_566364.4	Gene:	AgaP_AGAP000063 / 1272212	VectorBaseID:	AGAP000063	Length:	564	Species:	Anopheles gambiae

Alignment Length:	195	Identity:	54/195 - (27%)
Similarity:	78/195 - (40%)	Gaps:	49/195 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 DIAPTS------PAAAAAATSQN-GAHGHGGGN-GQG----------NASAGSNGKRKRSWSRAV 301
            |:.|.|      |.|....|:.: |..|.|.|. |||          |.:...:.|||...:|..
Mosquito   223 DVKPMSDDGTKNPFAKHCFTNLDAGVPGAGTGTPGQGGPGTKQVFVDNDTERLSLKRKLQRNRTS 287

  Fly   302 FSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLTDAQ-----VKVWFQNRRMKWRHTRENLK 358
            |:..|.:.||.:|::..|   ||   |.:|:::.||.:|:     ::|||.|||.|||.
Mosquito   288 FTVDQIEFLEKEFERTHY---PDVFSRERLSSKTNLPEARIQVSYIEVWFSNRRAKWRR------ 343

  Fly   359 SGQEKQPSAVPESGGVFKTSTPSGDGTPQEALDYSSDSCSSVDL------------SEQADEDDN 411
              :|||.|.....|.....:..:.......|:...:.|.||..|            |....||.|
Mosquito   344 --EEKQRSQAVSEGSSSAAAAAAAAAAAAAAVAVQNASISSCSLNLTAPLVSHVYDSNMCVEDSN 406

Fly 412 411
Mosquito 407 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/60 (35%)
AgaP_AGAP000063	XP_566364.4	PAX	7..131	CDD:128645
AgaP_AGAP000063	XP_566364.4	Homeobox	285..342	CDD:278475	21/59 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910