DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment H2.0 and AgaP_AGAP000190

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_310944.5	Gene:	AgaP_AGAP000190 / 1272074	VectorBaseID:	AGAP000190	Length:	493	Species:	Anopheles gambiae

Alignment Length:	217	Identity:	63/217 - (29%)
Similarity:	89/217 - (41%)	Gaps:	60/217 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 HHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQ--QQQRFLGKTPQQLLDIAPTS- 260
            ||||.||    |.||    |:|   |||..||..|.....|.  ::....|.|....:|.|...
Mosquito   128 HHHHHHH----HHQH----HHS---SALHEPLEKLKLWAETGDFRENSHTGMTSVSSIDHAQMGF 181

  Fly   261 PAAA-------------------AAATSQNGAHGHGGGNGQGNASAGS--------------NGK 292
            ||::                   |:..::|.:.|....:|.|:.:.|:              ..|
Mosquito   182 PASSPRNRSSRDRKNDVSRCINEASVKTENLSSGMSHEDGTGSVAPGTTIQQDGTDGTKNDKKNK 246

  Fly   293 RKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTREN- 356
            |:|. .|..|::.|...||..|.:.:|.....|.::|...|||:|:|:|||:|||.|||....|
Mosquito   247 RQRR-QRTHFTSQQLHELEQTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNQ 310

  Fly   357 --------LKSG---QEKQPSA 367
                    .|:|   |..||.|
Mosquito   311 MNAIAAADFKNGFGPQFVQPFA 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/52 (40%)
AgaP_AGAP000190	XP_310944.5	Homeobox	252..304	CDD:278475	21/51 (41%)
AgaP_AGAP000190	XP_310944.5	OAR	445..460	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910