DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment H2.0 and AgaP_AGAP011134

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_309513.3	Gene:	AgaP_AGAP011134 / 1270792	VectorBaseID:	AGAP011134	Length:	501	Species:	Anopheles gambiae

Alignment Length:	211	Identity:	51/211 - (24%)
Similarity:	64/211 - (30%)	Gaps:	67/211 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 LGKTPQQLLDIAPTS------------PAAAAAATSQN-GAHG--HGGG---------------- 279
            |||.|..:.|....|            |...|...|.. ||.|  ||.|
Mosquito   143 LGKGPHPMTDSLMGSASEDEDEEDQMRPGVLAGLVSGGAGAAGLHHGDGPLGASDLSVQSMSTDS 207

  Fly   280 ------NGQG---------------NASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKP 323
                  :.||               |.|.......||...|......|.:.|:..|.|....|:.
Mosquito   208 KTGHDDSDQGSLDGDPDCRGDSQAENKSPDDGAGSKRRGPRTTIKAKQLEVLKNAFSQTPKPTRH 272

  Fly   324 DRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESGGVFK------TSTPSG 382
            .|.:||....|....::|||||:|.|.|..::....|:.      |..||..|      ..:|.|
Mosquito   273 IREQLAKETGLPMRVIQVWFQNKRSKERRLKQLTSMGRG------PFFGGARKMRGFPMNLSPGG 331

  Fly   383 ---DGTPQEALDYSSD 395
               .|.|..|.|...|
Mosquito   332 LDEPGFPYFAADGKFD 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	17/52 (33%)
AgaP_AGAP011134	XP_309513.3	LIM1_Lhx1_Lhx5	27..78	CDD:188753
		LIM2_Lhx1_Lhx5	86..141	CDD:188761
		Homeobox	247..300	CDD:278475	17/52 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910