DRSC/TRiP Functional Genomics Resources

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Protein Alignment H2.0 and DBX1

DIOPT Version :9

Sequence 1:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001025036.2 Gene:DBX1 / 120237 HGNCID:33185 Length:343 Species:Homo sapiens


Alignment Length:316 Identity:96/316 - (30%)
Similarity:129/316 - (40%) Gaps:91/316 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 LFPG---PYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQ 211
            :|||   |...|.|:|||||       ..|.|             |..|.....|.....:.|.:
Human     2 MFPGLLAPPAGYPSLLRPTP-------TLTLP-------------QSLQSAFSGHSSFLVEDLIR 46

  Fly   212 QHKPP---PHNSTTASALLAPLHSLTSLQLTQ--------------------------QQQRFLG 247
            ..:||   |.:..|||  ::|........||.                          .:..||.
Human    47 ISRPPAYLPRSVPTAS--MSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLK 109

  Fly   248 KTPQQLLDIAP---TSPAAAAAATSQNGAHGHGGGNGQ------------------GNAS--AGS 289
            .....:|...|   ||||...:...:..|..:..|:.|                  |..|  ..:
Human   110 FGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAA 174

  Fly   290 NGKRKRSW-SRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHT 353
            .||.:|.. .|||||::|||.||..||:||||:||||:||||:|.|.|:|||:||||||||||::
Human   175 RGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNS 239

  Fly   354 --RENLKSG---QEKQPSAV---PE-----SGGVFKTSTPSGDGTPQEALDYSSDS 396
              ||.|.||   ::..|:.:   |:     ..|........|.|:|...|.|.:.|
Human   240 KERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASS 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2.0NP_523488.2 Homeobox 298..351 CDD:278475 38/52 (73%)
DBX1NP_001025036.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 56..100 6/45 (13%)
Homeobox 184..237 CDD:278475 38/52 (73%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..343 14/56 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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