DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and nyap2

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002937141.3	Gene:	nyap2 / 100496387	XenbaseID:	XB-GENE-1012710	Length:	716	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	50/245 - (20%)
Similarity:	78/245 - (31%)	Gaps:	105/245 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SAASMEQSMPENLST-------HMYGECEVNPTLAKCPDPVNVDHEL--------PTKESCASTT 55
            |::...||.|.:.||       |.|.:|.     :..|.||::...|        |..||..:.:
Frog   402 SSSGHSQSSPPHPSTMYRTQSPHGYPKCH-----SASPSPVSMGRSLTPLSLKRPPPYESVHTGS 461

  Fly    56 IVSTSPTSATSTTKVKLSFSVDRLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANA 120
            :..:||:...||.:            :.|:|....:||:.:..|                ||::.
Frog   462 LSRSSPSVPHSTVR------------NSPQEGKSVNSSTSTYNS----------------SQSSL 498

  Fly   121 ESRRFGHATLPPTFTPTSSHTYPFVGLDKLFPGPYMDYKSVLR---------------PTPIRAA 170
            .||           ||||    |...|..||...    :|:||               |..|:..
Frog   499 RSR-----------TPTS----PLEELSNLFTSG----RSLLRRPSSGRRSKEPSEKPPDEIKVR 544

  Fly   171 EHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNS 220
            .|:....|.|           :.::...||            ..||..:|
Frog   545 SHSTEPLPKL-----------ENKERVVHH------------SSPPSRDS 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475
nyap2	XP_002937141.3	NYAP_N	51..421	CDD:406008	6/18 (33%)
nyap2	XP_002937141.3	NYAP_C	464..716	CDD:406017	34/178 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910