DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and alx4

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_004913406.1	Gene:	alx4 / 100493396	XenbaseID:	XB-GENE-853003	Length:	376	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	62/231 - (26%)
Similarity:	96/231 - (41%)	Gaps:	45/231 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 QHQQHH-HHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAP 258
            ::|.|| .||....||:.|..|....|.:.....:|...|  :....::......:..|.:|
Frog    86 KYQAHHPSHQQQQSHLYMQSTPCKSPSDSLKVQDSPGDPL--IPCYAKESALTPNSDHQGMD--- 145

  Fly   259 TSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKP 323
             |....:..|:..|:...|.|:...:.:...:.|.|:..:|..|::.|.:.||..||:..|   |
Frog   146 -SGYITSKETAGKGSQDRGSGDLPMDKTESESNKGKKRRNRTTFTSYQLEELEKVFQKTHY---P 206

  Fly   324 D---RRKLAARLNLTDAQVKVWFQNRRMKWR---------HTRENLKSGQE-------------K 363
            |   |.:||.|.:||:|:|:|||||||.|||         ..|.:..|..|             :
Frog   207 DVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSSAYELPLLTRAENYAQIQ 271

  Fly   364 QPSAVPESGGVFKTSTPSGDGTPQEALDYSSDSCSS 399
            .||.:..:||          |:|..|.....|:.||
Frog   272 NPSWIGNNGG----------GSPVPACVVPCDTVSS 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	26/55 (47%)
alx4	XP_004913406.1	COG5576	120..266	CDD:227863	42/154 (27%)
		Homeobox	185..238	CDD:365835	27/55 (49%)
		OAR	352..370	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910