DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and arx

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002933659.1	Gene:	arx / 100486727	XenbaseID:	XB-GENE-483940	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	222	Identity:	70/222 - (31%)
Similarity:	93/222 - (41%)	Gaps:	78/222 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 QKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAP-----LHSLTSLQLTQQQQRFLGKTPQ 251
            |:|||.|....|      .||.:|||...|.|.  |:|     |||..:
Frog   235 QEQQHPQFQSQQ------SQQQQPPPGCGTDAE--LSPKEELMLHSSDA---------------- 275

  Fly   252 QLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNA--SAGSNG-----KRKRSWSRAVFSNLQRKG 309
                                     .|.:|:.:.  ||||:.     |||:...|..|::.|.:.
Frog   276 -------------------------DGKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEE 315

  Fly   310 LEIQFQQQKYITKPD---RRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPES 371
            ||..||:..|   ||   |.:||.||:||:|:|:|||||||.||| .||  |:|.:.....:|..
Frog   316 LERAFQKTHY---PDVFTREELAMRLDLTEARVQVWFQNRRAKWR-KRE--KAGAQTHAPGLPFP 374

  Fly   372 GGVFKTSTPSG---DGTP----QEALD 391
            |.: ..|.|.|   |.:|    ..|||
Frog   375 GPL-SASHPLGPYLDASPFPPHHPALD 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/55 (49%)
arx	XP_002933659.1	Homeobox	305..358	CDD:365835	29/56 (52%)
arx	XP_002933659.1	OAR	500..518	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910