DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and pax9

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002935394.1	Gene:	pax9 / 100485934	XenbaseID:	XB-GENE-482238	Length:	360	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	47/249 - (18%)
Similarity:	73/249 - (29%)	Gaps:	119/249 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 QQHHH--HQHHP--------KHLHQQHKP---------PPHNSTTASALLAP-----LHSLTSL- 236
            ||:|:  |:.||        .||:....|         ||...:....:..|     .||:|.:
Frog   136 QQNHYESHKQHPAAASALPYNHLYSYPSPIAAGAKVPTPPGMPSIPGTMGMPRTWPSSHSVTDIL 200

  Fly   237 ---QLTQQQQRFLGKTPQQLLDIAPTSP---------AAAAAATSQNGAHGHGGGNGQGNASAGS 289
               .:|.|              ::.|||         ::.:..|.|:..|
Frog   201 GIRSITDQ--------------VSDTSPYPSPKLEEWSSLSRNTFQSAQH--------------- 236

  Fly   290 NGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTR 354
                       |.:.|::..||   |:.||      .:.|:.|......|..
Frog   237 -----------VLNGLEKSSLE---QEVKY------SQSASGLPAVSGFVAA------------- 268

  Fly   355 ENLKSGQEKQPSAVPESGGV-FKTSTPSG----------DGTPQEALDYSSDSC 397
                ||....|:..|.|..: :.|:.|:|          .|||     .|..||
Frog   269 ----SGMTPYPTTAPVSPYMAYSTAAPTGYVTGHGWQHTGGTP-----LSPHSC 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	10/52 (19%)
pax9	XP_002935394.1	PAX	6..131	CDD:238076
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910