DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment H2.0 and arxb

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002667096.1	Gene:	arxb / 100329907	ZFINID:	ZDB-GENE-121109-2	Length:	385	Species:	Danio rerio

Alignment Length:	232	Identity:	68/232 - (29%)
Similarity:	98/232 - (42%)	Gaps:	52/232 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 PTLAT----NALLRFHQHQKQQHQQH-----HHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSL 233
            |||.:    :::|......|.|...|     |.|.|.|..|.:...|...:||..:|  .|
Zfish    20 PTLLSSYCIDSILGRKSPLKVQETPHSLWPLHPHMHLPPKLRRPFAPLTDSSTDETA--GP---- 78

  Fly   234 TSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGN--GQGNA----------- 285
               :|.|.....|..|...:::|:........|:......:...|.:  |:.|.
Zfish    79 ---RLLQTACEKLKITEASIVNISRAGSYQEHASCKNTPINEEEGADICGETNVTLKQEREAFLK 140

  Fly   286 -------SAGSNG-----KRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPD---RRKLAARLNLT 335
                   ||||:.     |||:...|..|::.|.:.||..||:..|   ||   |.:||.||:||
Zfish   141 NSEETSLSAGSDTEDGMLKRKQRRYRTTFTSYQLEELERAFQKTHY---PDVFTREELAMRLDLT 202

  Fly   336 DAQVKVWFQNRRMKWRHTRENLKSGQEKQPSAVPESG 372
            :|:|:|||||||.||| .||  |.|.:....::..||
Zfish   203 EARVQVWFQNRRAKWR-KRE--KVGVQPHTLSLHYSG 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	27/55 (49%)
arxb	XP_002667096.1	Homeobox	166..218	CDD:278475	27/54 (50%)
arxb	XP_002667096.1	OAR	351..368	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910