DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and chn1

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_012825384.1	Gene:	chn1 / 100038142	XenbaseID:	XB-GENE-852930	Length:	459	Species:	Xenopus tropicalis

Alignment Length:	143	Identity:	33/143 - (23%)
Similarity:	45/143 - (31%)	Gaps:	51/143 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DRLL-GSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANAESRRFGHATLPPTFTPTSSH 140
            |:|| |:|.....|:|...|.|.:.                     :.|||:.|..........|
Frog    60 DQLLSGAEGSYLIRESQRQPGTYTL---------------------ALRFGNQTRNFRLYYDGKH 103

  Fly   141 TYPFVGLDKLFPG-----------PYMDYKSVLRPTPIRAAEHAA-----PTYPTLATNALLRFH 189
               ||| :|.|..           .|::.|         |||:.|     |.|..:....|.|..
Frog   104 ---FVG-EKRFESIHDLVTDGLITLYIETK---------AAEYIAKMTINPIYEHIGYTTLNREP 155

  Fly   190 QHQKQQHQQHHHH 202
            .|:||.......|
Frog   156 AHKKQMPALREAH 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475
chn1	XP_012825384.1	SH2_a2chimerin_b2chimerin	42..128	CDD:198215	20/92 (22%)
		C1_1	206..255	CDD:365894
		RhoGAP_chimaerin	266..459	CDD:239837
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900