Protein Alignment CG9098 and bcar3

DIOPT Version :9

• Sequence 1: NP_608979.2
• Gene: CG9098 / 33840
• FlyBaseID: FBgn0031762
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: XP_021333970.1
• Gene: bcar3 / 570610
• ZFINID: ZDB-GENE-080513-4
• Length: 918
• Species: Danio rerio
• Alignment Length: 1002
• Identity: 302/1002 - (30%)
• Similarity: 442/1002 - (44%)
• Gaps: 207/1002 - (20%)

  Fly    46 MSISEWLDLLEL--------QQYEGNLQEFSTVDDVVDITDKELKQFGVRG-AHRQRMVNSLLGV 101
            ||||:||..|.|        ::|:| ::..|...|::.:|:.:|...||:. .||..:::|:..:
Zfish     4 MSISKWLSQLGLPQYCILFDEEYDG-VEVKSAHTDLLHLTEMDLLGLGVQSRLHRIHILSSIQVL 67

  Fly   102 R---AKRRQSMNLEA-MSSAPR--AVPRRKNSCPLV----YLGENPQ--DMAGSGDSG------- 147
            |   .||...|..|. .||.||  .|.|:   |||.    .|...|:  :|..||..|
Zfish    68 RERETKRELRMMAEGRFSSLPRNMHVGRQ---CPLASSMDLLSSRPELSEMPVSGYQGISIHGTL 129

  Fly   148 PGVITTKSGKVLKQLTFD----ETSTIY---EELRPRSKCNSP--HWAIED------SRMEGYGS 197
            |....|.:|..:||...:    ..:..|   ..|.|     ||  |..||:      .|.:...|
Zfish   130 PRKKKTTTGSPVKQWEVNGNVGSLAAPYPGRHRLPP-----SPLIHNIIEEHQTFCSDRKQSRNS 189

  Fly   198 SNATTPLATAQPS--------PSEQQEAIALKKALEWELSLDARELRSHAWYHGALPRQRAEEIV 254
            :.....:...:.|        |.|:     |::.||.||.|.:.|.|||||||||:|||.||.:|
Zfish   190 AGMDPTMEYVKFSRDKYILDGPPEK-----LRRELEEELKLSSEEPRSHAWYHGAIPRQVAENLV 249

  Fly   255 QREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYERVQYQFEEDAFDTVPDLITF 319
            ||:||||:||..|.|.||||:|:.|.:..||.:||.|:.....|.||||.||::.||::|.|:.:
Zfish   250 QRDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRVVAMNEAYSRVQYLFEKEGFDSIPALVRY 314

  Fly   320 YVGSGKPISSASGALIQFPCNRTYPLSFYGHKI-VGNQLHTQMLAG-LRGLSPLNSPMGSNGAVG 382
            |||:.:|:|...||:|..|.||..||.....|. ||:   .::.|| |...|..:..:..|...|
Zfish   315 YVGNREPVSEVIGAIIFQPINRALPLRCLEEKYGVGS---IRVEAGYLERKSLTSKRLSLNIMNG 376

  Fly   383 AGMNATFRFEPQQQQQQQLSPMAGSPASPHCSPPRARREVPPPPRLPCKKQQRSQSLTPAQAMLV 447
            .|.:.|.      .:...||......:.|.|......|      |.|.|..| |:|..|
Zfish   377 HGQDHTL------SRGNLLSNKDKCGSQPACLNHVQER------RRPLKTHQ-SESFLP------ 422

  Fly   448 SNINKLQEQQLQMQELENGNGNGIMRFQTIARCNPT-----------------SEQHLESKFTTH 495
              |....:.|:|..|.:....:.:.|..:....:||                 |:..|..|
Zfish   423 --IGSRPQAQVQHMEHQPCPKSPVFRTGSEPALSPTVPRRMAFDTLPGEAIRGSDSQLCPK---- 481

  Fly   496 SLPRPNTSAAHALRQQAVARISSLARNCSLDSPSDSRPPSPPPKPRKEPMAAVLAYQASGSDSGN 560
              |.|..|....:|...:..:.:|.           .||.||.||.|...:  |..|.|||...:
Zfish   482 --PPPKPSKVPTVRVPCIPALKTLV-----------VPPVPPVKPHKHRPS--LQQQQSGSPEMS 531

  Fly   561 GSGDSALGDACEASVQRGVIIKNP------RFMTTSVSNGTLKSFTEFDVLAAEEELFTMAIEEV 619
                     .||.|         |      ..|.:..:||.::.......:..:...:..|||.:
Zfish   532 ---------YCELS---------PCSPADWEKMNSLQANGYVERLKTDGSIKLDRSSYHNAIEAL 578

  Fly   620 KTASKFDFE-----------------------------NFVTLLLPSVENKPLDGDALNTFKMML 655
            ...|:.|.|                             ||  .|||. |||||:...|...|.:|
Zfish   579 DNDSEEDTEEDADKEQNGKKAFQKPVFETESAFRPANVNF--RLLPK-ENKPLEMTVLKKAKELL 640

  Fly   656 LETGPKLLAEHITRID--IALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIERTQCIKLMV 718
            :...||.:|:||.:.|  :|..|......:......|||||:|||||:..|.|:|||...:.:.|
Zfish   641 VSQDPKTIAKHILQADCQVARILNVSEEVKGQMGVSSGLELVTLPHGRQLRLDLIERHNTMAIGV 705

  Fly   719 AVTILTCQTDL-DRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQYT 782
            ||.||.|...| :||..|::.|.:|:|.|.::|:|:.|.:||..|.|.||.:||..|..||::||
Zfish   706 AVDILGCTGSLEERAATLNRIILVALELKDSMGDLYAFSSIMKALDMPQITRLDHTWTSLRRKYT 770

  Fly   783 DSAFTFEAKLRPTLSIMNEASNPQAP--NTTVPHVLLYALLIDRPVMDIINHSNIDDRPALYHTC 845
            .:|..:|..|:|....:.| ...:.|  |.:||  ||..||            .:.:|||:....
Zfish   771 QTAIIYEKSLKPFYKGLYE-GGAEIPLSNASVP--LLMPLL------------TLMERPAVTFEG 820

  Fly   846 IAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADAFRTEFHVKFL 910
            :..||:  .|.|..|.|:||:.:|...:|.:.|..||:.||:|..|..|.|  :..||:|.::.|
Zfish   821 MDVWEN--TDQGCEIMFRHLEGARAVARNADTYTCNAQRILQDFQPHEDML--EILRTDFQLRLL 881

  Fly   911 WGSSGATAKAEDRHNKLEKVLTLMADK 937
            |||.||..:..:|::|.:.:||.::.|
Zfish   882 WGSRGAAVEQTERYDKFKLILTALSRK 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9098	NP_608979.2	SAM_1	43..102	CDD:278937	19/64 (30%)
		SAM	47..103	CDD:197735	19/67 (28%)
		SH2_BCAR3	233..367	CDD:198200	67/135 (50%)
		RasGEF	660..>797	CDD:295324	57/139 (41%)
bcar3	XP_021333970.1	SAM_1	3..68	CDD:306919	19/64 (30%)
		SH2_BCAR3	231..362	CDD:198200	66/133 (50%)
		RasGEF	644..>783	CDD:321950	56/138 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596314
Domainoid	1	1.000	102	1.000	Domainoid score	I6820
eggNOG	1	0.900	-	-		E1_28HJ9
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2613
OMA	1	1.010	-	-		QHG49555
OrthoDB	1	1.010	-	-		D138275at2759
OrthoFinder	1	1.000	-	-		FOG0003062
OrthoInspector	1	1.000	-	-		otm25757
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2423
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870